Estudios Científicos

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Efficacy and Safety of Long-term Corticosteroid Eye Drops after Penetrating Keratoplasty A Prospective, Randomized, Clinical Trial.

Shimazaki J, Iseda A, Satake Y, Shimazaki-Den S.
Source
Department of Ophthalmology, Tokyo Dental College Ichikawa General Hospital, Chiba, Japan; Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.

Abstract
PURPOSE:

Endothelial rejection remains a major cause of graft failure after penetrating keratoplasty (PKP). Topical corticosteroids are the gold standard for preventing rejection; however, protocols for corticosteroid treatment have been diverse. The aim of the present study was to examine the efficacy and safety of long-term use of corticosteroid eye drops after PKP in a randomized, clinical trial.

Ketorolac therapy for the prevention of acute pseudophakic cystoid macular edema: a systematic review.

Abstract

To assess the effectiveness of ketorolac vs control for prevention of acute pseudophakic cystoid macular edema (CME). The following databases were searched: Medline (1950-June 11, 2011), The Cochrane Library (Issue 2, 2011), and the TRIP Database (up to 11 June 2011), using no language or other limits. Randomized controlled clinical trials (RCTs) were included that consisted of patients with acute pseudophakic cystoid macular edema, those comparing ketorolac with control, and those having at least a minimum follow-up of 28 days.

Multiple endpoint analysis of BAC-preserved and unpreserved antiallergic eye drops on a 3D-reconstituted corneal epithelial model.

Source
INSERM, UMR_S968, Institut de la Vision, Paris, France.

PURPOSE:
To compare the effects of benzalkonium chloride (BAC)-preserved and unpreserved antiallergic eye drops on the human 3D-reconstituted corneal epithelial model (3D-HCE).

Preservatives in eyedrops: the good, the bad and the ugly.

Source
Department of Ophthalmology III, Quinze-Vingts National Ophthalmology Hospital, INSERM, U968, UPMC Univ Paris 06, UMR_S 968, Institut de la Vision, CNRS, UMR_7210, Paris F-75012, France. baudouin@quinze-vingts.fr

Carboxymethylcellulose binds to human corneal epithelial cells and is a modulator of corneal epithelial wound healing.

Garrett Q, Simmons PA, Xu S, Vehige J, Zhao Z, Ehrmann K, Willcox M.
Source
Institute for Eye Research, University of New South Wales, Sydney, NSW 2052, Australia. q.garrett@ier.org.au

Abstract
PURPOSE:
In this study, the ability of carboxymethylcellulose (CMC), used in artificial tear formulations, to interact with corneal-epithelial-cells (HCECs) and facilitate corneal epithelial wound healing was investigated.

Efficacy of sodium carboxymethylcellulose in the treatment of dry eye syndrome.

Bruix A, Adán A, Casaroli-Marano RP.
Source
Servicio de Oftalmología, Hospital de la Santa Creu i Sant Pau, Facultad de Medicina, Universidad Autónoma de Barcelona, Spain.

Abstract
AIM:
To assess the efficacy of sodium carboxymethylcellulose in the treatment of dry eye.

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